Machine Learning Opportunities in the Explosion of Personalized Precision Medicine

We have reached the take off point in the generation of massive datasets from individuals and across populations, both of which are necessary for personalized precision medicine. I will give an example of my N=1 self-study, in which I have my human genome as well as multi-year time series of my gut microbiome genomics and over one hundred blood biomarkers. This is now being augmented with time series of my metabolome and immunome. These are then compared with hundreds of healthy people’s gut microbiomes, revealing major shifts between health and disease. Multiple companies and organizations will soon be carrying out similar levels of analysis on hundreds of thousands of individuals. Machine learning techniques will be essential to bring the patterns out of these exponentially growing datasets.