As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples.
Smarr, Larry, Marc Jaffrey, Michael Dushkoff, Brynn Taylor, Pilar Ackerman, Mehrdad Yezdani, and Weizhong Li. "EXTRACTING INSIGHTS ON THE DYNAMIC HEALTH-DISEASE TRANSITIONS IN THE HUMAN GUT MICROBIOME." (2018).