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Larry Smarr
Larry Smarr
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  1. Home /
  2. Publications /
  3. Recent Publications
The National Research Platform: Stretched, Multi-Tenant, Scientific Kubernetes Cluster
Journal Articles  |   July 18, 2025

The National Research Platform: Stretched, Multi-Tenant, Scientific Kubernetes Cluster

Critical operational insights are discussed, including security enhancements using Kubernetes-integrated threat detection, extensive monitoring, and comprehensive accounting systems.
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Distributed Systems
Longitudinal flux balance analyses of a patient with episodic colonic inflammation reveals microbiome metabolic dynamics
Journal Articles  |   July 12, 2023

Longitudinal flux balance analyses of a patient with episodic colonic inflammation reveals microbiome metabolic dynamics

We report the first use of constraint-based microbial community modeling on a single individual with episodic inflammation of the gastrointestinal tract.
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Microbial CommunitiesMicrobiomePersonalized Medicinequantifying my body
Towards a Dynamic Composability Approach for using Heterogeneous Systems in Remote Sensing
Journal Articles  |   October 11, 2022

Towards a Dynamic Composability Approach for using Heterogeneous Systems in Remote Sensing

Altintas, Ilkay, et al. "Towards a dynamic composability approach for using heterogeneous systems in remote sensing." 2022 IEEE 18th International Conference on e-Science (e-Science). IEEE, 2022.
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Environmental Observatories
Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity
Journal Articles  |   May 1, 2021

Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity

Many studies have investigated the role of the microbiome in inflammatory bowel disease (IBD), but few have focused on surgery specifically or its consequences on the metabolome.
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Gastrointestinal SurgeryInflammatory Bowl DiseaseMicrobial CommunitiesMicrobiome
De Novo Peptide Sequencing Reveals Many Cyclopeptides in the Human Gut and Other Environments
Journal Articles  |   January 22, 2020

De Novo Peptide Sequencing Reveals Many Cyclopeptides in the Human Gut and Other Environments

We present a computational pipeline for automated analysis and discovery of cyclic and branch cyclic peptides (cyclopeptides).
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Microbial CommunitiesMicrobiome
Phylogenomics of 10,575 Genomes Reveals Evolutionary Proximity Between Domains Bacteria and Archaea
Journal Articles  |   December 2, 2019

Phylogenomics of 10,575 Genomes Reveals Evolutionary Proximity Between Domains Bacteria and Archaea

Nature Communications 10, 5477. (2019).
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Microbial CommunitiesMicrobiome
Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads
Journal Articles  |   October 31, 2019

Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads

As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples.
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MetagenomicsMicrobial CommunitiesMicrobiomeQuantified Self
The Evolution of Bits and Bottlenecks in a Scientific Workflow Trying to Keep up With Technology: Accelerating 4D Image Segmentation Applied to NASA data
Journal Articles  |   September 27, 2019

The Evolution of Bits and Bottlenecks in a Scientific Workflow Trying to Keep up With Technology: Accelerating 4D Image Segmentation Applied to NASA data

Proceedings of the 15th IEEE International eScience Conference (2019).
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