Quantifying My Body
3D Medical Imaging Pilot to Improve Surgical Outcomes for Patients with Crohn’s Disease
Pilot study to create a 3D Medical Imaging tool to personalize clinical decisions and improve surgical outcomes for patients with Crohn’s disease.
Longitudinal flux balance analyses of a patient with episodic colonic inflammation reveals microbiome metabolic dynamics
We report the first use of constraint-based microbial community modeling on a single individual with episodic inflammation of the gastrointestinal tract.
Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn’s Disease
mSystems 4:e00337-18. (2019).
Extracting Insights On The Dynamic Health-Disease Transitions In The Human Gut Microbiome
Smarr, Larry, Marc Jaffrey, Michael Dushkoff, Brynn Taylor, Pilar Ackerman, Mehrdad Yezdani, and Weizhong Li. "EXTRACTING INSIGHTS ON THE DYNAMIC HEALTH-DISEASE TRANSITIONS IN THE HUMAN GUT MICROBIOME." (2018).
Metagenomics-Based, Strain-Level Analysis of Escherichia coli From a Time-Series of Microbiome Samples From a Crohn’s Disease Patient
Frontiers in Microbiology. Vol 9, article 2559. (2018).
Creating a 3D microbial and chemical snapshot of a human habitat
Nature Scientific Reports, vol.8: 3669. (2018).
Tracking Human Gut Microbiome Changes Resulting from a Colonoscopy
L. Smarr, E. R. Hyde, D. McDonald, W. J. Sandborn, R. Knight. Methods of Information in Medicine. 56(6):442-447 (2017).
Using Machine Learning to Identify Major Shifts in Human Gut Microbiome Protein Family Abundance in Disease
Proceedings Of The 2016 IEEE International Conference On Big Data. M. Yazdani, B. C. Taylor, J. W Debelius, W. Li, R. Knight, and L. Smarr. (2016).
Using Topological Data Analysis to find discrimination between microbial states in human microbiome data
Mehrdad Yazdani, Larry Smarr and Rob Knight. (2016).
Quantifying Your Body: A How-to Guide From A Systems Biology Perspective – Biotechnology Journal
Biotechnology Journal. pages 980-991. (2012).
An Evolution Toward A Programmable Universe – The New York Times
Using this data, the planetary computer will be able to build a computational model of your body and compare your sensor stream with millions of others. Besides providing early detection of internal changes that could lead to disease, cloud-powered voice-recognition wellness coaches could provide continual personalized support on lifestyle choices, potentially staving off disease
Quantified Health: A 10-year Detective Story Of Digitally Enabled Genomic Medicine
Larry Smarr, with commentary by Mark Anderson, published as a Special Letter in the Strategic News Service Newsletter, September 30, 2011
How I Improved My Health By Changing My Eating, Exercise, And Stress Management Habits: An Annotated Reading List
Larry Smarr, Requested by Mark Anderson, CEO Strategic News Service For Distribution to the Future in Review 2011 Attendees
Report on the Biomedical Information Science and Technology Initiative
Prepared by the Working Group on Biomedical Computing, Advisory Committee to the Director, National Institutes of Health, (Co-Chairs, L. Smarr and D. Botstein). June 3, 1999.
Mednet: A Model For Applying Supercomputing Technologies To Medical Biostereometrics
State-of-the-art computational tools and advanced technologies, accessible through MEDnet, can optimize biostereometric data computational tools, and advanced technologies, accessible through MEDnet, can optimize biostereometric data collection, data transfer, and the reconstruction of various metrics and images.Human Life Extension: The State of the Art – Future In Review
April 10, 2024 “The Technology Behind Life Extension in Action” Renowned science author and journalist David Ewing Duncan takes the FiRe audience on a very personal journey into human life extension. Experience the science of human longevity in action, with personalized-medicine pioneer Larry Smarr and Human Longevity president and chief innovation officer David Karow.Will Supercomputers Create Virtual Maps of Your Body in the Future? – Seeker
Larry Smarr has been collecting 3D visualizations and detailed data on his body for almost a decade, amassing it all into a VR medical avatar of himself.Aspen Ideas Festival 2018 – The Man Who Saw Inside Himself
Larry Smarr believes in being the CEO of his own body, and for years, he has been measuring inputs and outputs.Future Patient/Future Doctor – Larry Smarr, PhD and Michael Kurisu, DO
Computer scientist Larry Smarr and osteopathic physician Michael Kurisu present a vision for healthcare that combines the best of allopathic and osteopathic medicine by using a more personalized, hands-on, systems-based approach to treating patients. They demonstrate this proof of concept with details on how Smarr diagnosed his own Crohn‚Äôs disease by using blood and stool […]FuturePatient – Larry Smarr, PhD
The full recording of computer scientist Larry Smarr presenting ten years of his personal health data on the Visualization Wall at his institute, Calit2 at UC San Diego.
The Man Who Saw Inside Himself – The Atlantic
For years, Larry Smarr has used a supercomputer to monitor his health and peer at his organs. Recently, he used his knowledge to help direct his own surgery.
The Quantified Patient Checks In – IEEE
Like eight-year-olds who can't let go of a good joke, Larry Smarr's nurses and doctors kept coming to him with the same question: "Have you passed gas yet?" Answering this question in the affirmative is, Smarr explains, deadpan, "the state of the art in 2017 in the medical community for deciding when your colon restarts".Look twice, cut once – University of California News
Before Sonia Ramamoorthy, M.D., chief of colon and rectal surgery at UC San Diego Health, took a scalpel to Larry Smarr, she first took a virtual tour of his large intestine. It encompassed an entire room.
Welcome to my colon: A tech pioneer turns to virtual reality to guide his own surgery – STAT News
Spend enough time with Larry Smarr and, chances are, he’ll invite you to step inside his colon.This UC San Diego Professor Planned His Surgery In Virtual Reality – KPBS
UC San Diego's Larry Smarr is the kind of guy who wears a Fitbit, monitors his sleep and has had his DNA sequenced. But he takes the whole self-tracking thing farther than most. He has mapped his internal organs in three dimensions. He even has a 3-D printed model of part of his colon.
Teaching Computers to Recognize Unhealthy Guts – SDSC’s ‘Gordon’ Supercomputer Assists in New Microbiome Study
January 18, 2017 - A new proof-of-concept study by researchers from the University of California San Diego has succeeded in training computers to “learn” what a healthy versus an unhealthy gut microbiome looks like based on its genetic makeup.
A Public Infrastructure For Data Access – Quantified Self
Larry Smarr’s major contributions to scientific progress are well known. A physicist and the founding director of the National Center for Supercomputing Applications (NCSA), he helped bring the power of computing to scientific research at a time when computers will still highly specialized instruments.
Health and data: can digital fitness monitors revolutionise our lives? – The Guardian
From granular microchips to voice analysis, health-tracking technology offers medical benefits but doubt persist about the quality and security of data gathered
Larry Smarr is the poster boy for wearable devices and the quantified self – The Sydney Morning Herald
May 10, 2015 Smarr, an astrophysicist and computer scientist, could be the world’s most self-measured man. For nearly 15 years, the professor at the University of California at San Diego has been obsessed with what he describes as the most complicated subject he has ever experimented on: his own body. Link to Article
The Revolution Will Be Digitized – Washington Post
Spearheaded by the flood of wearable devices, a movement to quantify consumers’ lifestyles is evolving into big business with immense health and privacy ramifications.
The Excrement Experiment – The New Yorker
But it was an inadvertent discovery in a stool analysis that led to Smarr's Crohn’s diagnosis and, eventually, to a new calling: as an evangelist for an impending medical revolution, “quantified health.”
From Quantified Self to Personalized Medicine – HPC Wire
November 6, 2014 - The University of Washington Computer Science and Engineering Distinguished Lecture series recently welcomed Calit2 luminary Larry Smarr to speak on a very interesting topic, bringing wellness into the digital age.Mind Brain Genome Microbiome: Conversation with Deepak Chopra
Deepak Chopra interviews Dr. Larry Smarr. We discussed everything from the origins of life, life in the universe, consciousness, mind brain genome, environment and the science of epigenetics. 04.23.2014.
The Quantified Computer Scientist: Larry Smarr on the Future of Medicine – Vox
Cast across the screens are Smarr’s insides, or at least the closest you can get when breaking down the microbiology of a human body into data. There are some 150 variables in boxes color-coded against their divergence from the norm
Larry Smarr: Where There Is Data There Is Hope – Quantified Self
“I never thought I would be getting into this business.” This is the first sentence in a mind-expanding talk by Larry Smarr about his self-tracking journey.The Human Laboratory: One Researcher’s Quest to Personalize Medicine with Larry Smarr
Larry Smarr talks with Mark Bowden about the drive to understand everything about his own body and how that kind of knowledge will become standard in the future. 11.26.2012.
Tracking your body with technology – CNN
“I am trying to respect my doctor by doing my part of the homework,” said Smarr, 63, of La Jolla, California.
The Measured Man – The Atlantic
Larry Smarr, an astrophysicist turned computer scientist, has a new project: charting his every bodily function in minute detail. What he's discovering may be the future of health care.Larry Smarr Quantified Health 3D
Larry Smarr discusses his efforts in the quantified self movement in this 3D clip shot in the Calit2 StarCAVE virtual reality environment.
Computing pioneer Larry Smarr and his quantified self – BoingBoing.net
June 22, 2012 I have the opportunity to chat with Larry with some frequency as he’s on the advisory board of Institute for the Future where I’m a researcher. I’m always intrigued by Larry’s stories of his quantified self practices. For years, Larry has been examining his own body at a very high resolution by […]Quantified Self – San Diego Union-Tribune
UCSD Physicist Larry Smarr explains Quantified Self and how he believes it could help lower the financial strains of health care. Video by Gary Robbins and David Brooks. 03.16.2012.
Innovator tracks everything his body does – San Diego Union-Tribune
“The bacteria in here contains more info than you’d find on a computer chip,” Smarr says. “It’s a window into your health. Within 10 years, people won’t dream of going to a doctor without first getting a sample like this.”
The Patient of the Future – MIT Technology Review
Internet pioneer Larry Smarr’s quest to quantify everything about his health led him to a startling discovery, an unusual partnership with his doctor, and more control over his life.Future Health – Quantified Self and the Future of Personal Health
The local San Diego Quantified Self meetup group working in collaboration with CALIT2, the Center for Wireless and Population Health Systems, and the West Wireless Health Institute brought together great panel discussion. 02.07.2012.
Calit2: Wireless health to drive preventative medicine – MobiHealthNews
Smarr said he's pushing the digital transformation of healthcare along with similar transformations in energy, the environment and "our culture" itself.